Zhang H, Ishii K, Shubata T, Ishii S, Hirano M, Lu Z, Takamura R, Kitano Ss, Miyachi H, Kageyama R,
Itakura E, Kobayashi T (2024) Fluctuation of lysosomal protein degradation in neural stem cells of the postnatal mouse brain. Development. 2024 Feb
15;151(4):dev202231.
Park SH, Lee SE, Jeon JH, Lee JH, Itakura E, Chang S, Choi WH, Lee MJ (2023) Formation of aggresomes with hydrogel-like characteristics
by proteasome inhibition. Biochim Biophys Acta Gene Regul Mech. 2023 Jun 1866(2):194932.
Chiba M, Yanagawa M,Oyama
Y, Harada S, Nemoto T,Matsuura A,Itakura E (2023) A novel autophagy inhibitor, bTBT, disturbs autophagosome
formation. Autophagy Rep. 2023 Apr 6;2(1):2194620.
Tomihari A, Kiyota M, Matsuura
A, Itakura E. (2023) Alpha 2-macroglobulin acts as a clearance factor in the lysosomal degradation of extracellular misfolded
proteins. Sci Rep. 2023 Mar 28;13(1):4680.
Ishii S, Chino H, Ode KL, Kurikawa Y, Ueda HR, Matsuura A, Mizushima N, Itakura E. (2023) CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy. Mol Biol
Cell. 2023 Apr 1;34(4):ar29.
Oya K, Matsuura A. (2022) Haploinsufficiency of the sex-determining genes at MATα
restricts genome expansion in Saccharomyces cerevisiae. iScience 2022 Aug 19; 25(8), 104783.
Date Y, Matsuura A, Itakura E. (2022)
Disruption of actin dynamics induces autophagy of the eukaryotic chaperonin TRiC/CCT. Cell Death Discov. 2022 Jan 25;8(1):37.
Tomihari A*, Chiba M*, Matsuura A,
Itakura E. (2021) Protocol for quantification of the lysosomal degradation of extracellular proteins into mammalian cells. Star
protocols, 2(4):100975 (*These authors contributed equally)
Uesugi R, Ishii S, Matsuura A, Itakura E. (2021) Labeling and Measuring Stressed Mitochondria Using a PINK1-Based Ratiometric Fluorescent Sensor. J Biol Chem.
297(5):101279
Pan Y, Liu Y, Fujii R, Farooq U, Cheng L, Matsuura A, Qi J, Xiang L. (2021) Ehretiquinone
from Onosma bracteatum wall exhibits antiaging effect on yeasts and mammals through antioxidative stress and autophagy induction. Oxid. Med. Cell.
Longev. 2021: 5469849
Tachibana H, Morioka T, Daino K, Shang Y, Ogawa M, Fujita M, Matsuura A, Nogawa H, Shimada Y,
Kakinuma S. (2020) Early induction and increased risk of precursor B-cell neoplasms after exposure of infant or young-adult mice to ionizing radiation. J. Rad. Res. 61:
648-656
Liu Q, Cheng L, Matsuura A, Xiang L, Qi J. (2020) Gentiopicroside, a secoiridoid glycoside from Gentiana rigescens Franch,
extends the lifespan of yeast via inducing mitophagy and antioxidative stress. Oxid. Med. Cell. Longev. 2020: 9125752
Itakura E, Chiba M, Murata T, Matsuura
A. (2020) Heparan sulfate is a clearance receptor for aberrant extracellular proteins. J Cell Biol. 219: e201911126
Otsubo K, Maeyashiki C, Nibe Y, Tamura A, Aonuma E, Matsuda H, Kobayashi M, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Torii S, Itakura E, Watanabe M, Oshima S. (2020) Receptor-Interacting Protein Kinase 3 (RIPK3) inhibits autophagic flux during necroptosis in intestinal epithelial
cells. FEBS Lett. 594: 1586-1594
Ishii S, Matsuura A, Itakura
E. (2019) Identification of a factor controlling lysosomal homeostasis using a novel lysosomal trafficking probe. Sci. Rep. 9: 11635
Miura A, Matsuura A. (2019) Phosphatase-dependent fluctuations in DNA-damage checkpoint
activation at partially defective telomeres. Biochem. Biophys. Res. Commun. 516: 133-137
Miura A, Itakura E, Matsuura A. (2019)
Reversible DNA damage checkpoint activation at the presenescent stage in telomerase-deficient cells of Saccharomyces cerevisiae. Genes Cells 24: 546-558
Ueda S, Ozaki R, Kaneko A, Akizuki R, Katsuta H, Miura A, Matsuura A, Ushimaru T.
(2019) TORC1, Tel1/Mec1, and Mpk1 regulate autophagy induction after DNA damage in budding yeast. Cellular Signaling 62: 109344
Lin Y, Kotakeyama Y, Li J, Pan Y, Matsuura A, Ohya Y, Yoshida M, Xiang L, Qi J. (2019) Cucurbitacin B exerts antiaging effects in yeast by
regulating autophagy and oxidative stress. Oxid. Med. Cell. Longev. 2019: 4517091
Takahashi K, Itakura E, Takano K, Endo, T. (2019) DA-Raf, a dominant-negative regulator of the Ras–ERK pathway, is essential for skeletal
myocyte differentiation including myoblast fusion and apoptosis. Exp. Cell Res. 376: 168–180
Baba M, Tomonaga S, Suzuki M, Maeda G, Takeda E, Matsuura A, Kamada Y, Baba N. (2019) A
nuclear membrane-derived structure associated with Atg8 is involved in the sequestration of selective cargo, the Cvt complex, during autophagosome formation in yeast.
Autophagy 15: 423-437
Takeda E, Matsuura A. (2018) A substrate localization model for the selective regulation of
TORC1 downstream pathways. Commun. Integr. Biol. 11: e1475830
Tatsumi T, Takayama K, Ishii S, Yamamoto A, Hara T, Minami N, Miyasaka N, Kubota T,
Matsuura A, Itakura E*, Tsukamoto S*. (2018) Forced lipophagy reveals that lipid droplets are
required for early embryonic development in mouse. Development 145: dev161893 (*co-corresponding authors)
Yamagishi Y, Oya K, Matsuura A, Abe H. (2018) Use of CK-548 and CK-869 as Arp2/3 complex
inhibitors directly suppresses microtubule assembly both in vitro and in vivo. Biochem. Biophys. Res. Commun. 496: 834-839
Takeda E, Jin N, Itakura E, Kira S, Kamada Y, Weisman LS, Noda T, Matsuura A. (2018) Vacuole-mediated selective regulation of TORC1-Sch9 signaling following oxidative stress. Mol. Biol. Cell 29: 510-522
Itakura E*, Chen C, de Bono M*. (2017) Purification of FLAG-tagged secreted proteins from mammalian cells. Bio Protoc. 7:
e2430 (*co-corresponding authors)
Takayama K, Matsuura A, Itakura E. (2017)
Dissection of ubiquitinated protein degradation by basal autophagy. FEBS Lett. 591: 1199-1211 (Selected as Editor's Choice)
Chen C, Itakura E, Nelson GM, Sheng M, Laurent P, Fenk LA, Butcher RA, Hedge RS, de Bono M. (2017) IL-17 is a neuromodulator of
Caenorhabditis elegans sensory responses. Nature 542: 43-48
Kinoshita N, Matsuura A, Fujiki Y. (2017) Peroxisome biogenesis: a novel inducible PEX19 splicing variant is involved in early stage
of peroxisome proliferation. J. Biochem. 161: 297-308
Yoshii SR, Kuma A, Akashi T, Hara T, Yamamoto A, Kurihara Y, Itakura E, Tsukamoto S, Shitara H, Eishi Y, Mizushima N. (2016) Systemic analysis
of Atg5-null mice rescued from neonatal lethality of transgenic ATG5 expression in neurons. Dev. Cell 39, 116-130
Itakura E, Zavodszky E, Shao S, Wohlever ML, Keenan RJ, Hegde RS. (2016) Ubiquilins chaperone and triage mitochondrial membrane proteins for
degradation. Mol. Cell 7: 21-33
Lin Y, Sun Y, Weng Y, Matsuura A, Xiang L, Qi J. (2016) Parishin from Gastrodia elata extends the lifespan of yeast via
regulation of Sir2/Uth1/TOR signaling pathway. Oxid. Med. Cell. Longev. 2016: 4074690
Maruyama Y, Ito T, Kodama H, Matsuura A. (2016) Availability of amino acids extends
chronological lifespan by suppressing hyper-acidification of the environment in Saccharomyces cerevisiae. PLoS ONE 11: e0151894
Kira S, Kumano Y, Ukai H, Takeda E, Matsuura A, Noda T. (2016) Dynamic relocation of the
Ego1/2/3 complex is regulated by Gtr1 and Gtr2. Mol. Biol. Cell 15: 382-396
Klionsky DJ, Itakura E, Matsuura A, et al. (2016) Guidelines for the use and interpretation
of assays for monitoring autophagy (3rd edition). Autophagy 12: 1-222
Satpute-Krishnan P, Ajinkya M, Bhat S, Itakura E, Hegde RS, Lippincott-Schwartz J. (2014) ER Stress-induced clearance of misfolded
GPI-anchored proteins via the secretory pathway. Cell 158: 522-533
Kishi-Itakura C, Koyama-Honda I, Itakura E, Mizushima N. (2014) Ultrastructural analysis of autophagosome organization using mammalian
autophagy-deficient cells. J. Cell Sci. 127: 4089-4102
Chen C, Itakura E, Weber KP, Hegde RS, de Bono M. (2014) An ER complexof ODR-4 and ODR-8/Ufm1 specific protease 2 promotes GPCR maturation by
a Ufm1-independent mechanism. PLoS Genetics 10: e1004082
Jiang P, Nishimura T, Sakamaki Y, Itakura E, Hatta T, Natsume T, Mizushima N. (2014) The HOPS complex mediates autophagosome-lysosome fusion
through interaction with syntaxin 17. Mol. Biol. Cell 25: 1327-1337
Sahani MH, Itakura E, Mizushima N. (2014) Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending
on transcriptional upregulation and autophagy-derived amino acids. Autophagy 10: 431-441
Tomida J, Itaya A, Shigechi T, Unno J, Uchida E,Ikura M, Masuda Y, Matsuda S, Adachi J, Kobayashi M, Meetie R, Maehara Y, Yamamoto K, Kamiya K, Matsuura A, Matsuda T, Ikura T, Ishiai M, Takata M. (2013) A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA crosslink
repair. Nucl. Acids Res. 41: 6930-6941
Matsui A, Kamada Y, Matsuura A. (2013) The role of autophagy in genome stability through
suppression of abnormal mitosis under starvation. PLoS Genetics 9: e1003245
Koyama-Honda I, Itakura E, Fujiwara TK, Mizushima N. (2013) Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome
formation site. Autophagy 9: 1491-1499
Itakura E, Kishi-Itakura C, Mizushima N. (2012) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with
endosomes/lysosomes. Cell 151: 1256-1269
Itakura E, Kishi-Itakura C, Koyama-Honda I, Mizushima N. (2012) Structures containing Atg9A and the ULK1 complex independently target
depolarized mitochondria at initial stages of Parkin-mediated mitophagy. J Cell Sci. 125: 1488-1499
Xiang L, Nakamura Y, Lim YM, Yamasaki Y, Kurokawa-Nose Y, Maruyama W, Osawa T, Matsuura A, Motoyama N, Tsuda L. (2011) Tetrahydrocurcumin
extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor. Aging 3: 1098-1109
Matsuura A, Matsui A. (2011) Control of telomere DNA replication: genetics, molecular
biology, and physiology. DNA Replication; Current Advances, pp.305-322, Intech.
Itakura E, Mizushima N. (2011) p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J
Cell Biol. 192: 17-27
Matsui A, Matsuura A. (2010) Cell size regulation during telomere-directed senescence in
Saccharomyces cerevisiae. Biosci. Biotechnol. Biochem. 74: 195-198
Itakura E, Mizushima N. (2010) Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.
Autophagy 6: 764-776
Itakura E, Mizushima N. (2009) Atg14 and UVRAG: Mutually exclusive subunits of mammalian Beclin 1-PI3K complexes. Autophagy
5: 534-536
Nakashima A, Maruki Y, Imamura Y, Kondo C, Kawamata T, Kawanishi I, Takata H, Matsuura A, Lee KS, Kikkawa U, Ohsumi Y, Yonezawa K, Kamada Y.
(2008) The yeast Tor signaling pathway is involved in G2/M transition via Polo-kinase. PLoS ONE 3: e2223
Itakura E, Kishi C, Inoue K, Mizushima N. (2008) Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and
UVRAG. Mol. Biol. Cell 19: 5360-5372
Itakura E, Sawada I, Matsuura A. (2005) Dimerization of the ATRIP protein through the
coiled-coil motif and its implication to the maintenance of stalled replication forks. Mol. Biol. Cell 16: 5551-5562
Takata H, Tanaka Y, Matsuura A. (2005) Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere
replication proteins in Saccharomyces cerevisiae. Mol. Cell 17: 573-583
Itakura E, Kajihara Takai K, Umeda K, Kimura M, Ohsumi M, Tamai K, Matsuura A. (2004)
Amino-terminal domain of ATRIP contributes to intranuclear relocation of the ATR-ATRIP complex following DNA damage. FEBS Lett. 577: 289-293
Itakura E, Umeda K, Sekoguchi E, Takata H, Ohsumi M, Matsuura A. (2004) ATR-dependent
phosphorylation of ATRIP in response to genotoxic stress. Biochem. Biophys. Res. Commun. 323: 1197-1202
Takata H, Kanoh Y, Gunge N, Shirahige K, Matsuura A. (2004) Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1
with telomeresin vivo. Mol. Cell 14: 515-522
Ono Y, Tomita K, Matsuura A, Nakagawa T, Masukata H, Uritani M, Ushimaru T, Ueno M. (2003) A novel allele of fission yeast rad11 that causes
defects in DNA repair and telomere length regulation. Nucl. Acids Res. 31: 7141-7149
Sekoguchi E, Sato S, Yasui A, Fukada S, Nimura Y, Aburatani H, Ikeda K, Matsuura A. (2003) A novel mitochondrial carnitine-acylcarnitine
translocase induced by partial hepatectomy and fasting. J. Biol. Chem. 278: 38796-38802
Kibe T, Tomita K, Matsuura A, Izawa D, Kodaira T, Ushimaru T, Uritani M, Ueno M. (2003) Fission yeast Rhp51 is required for the maintenance of
telomere structure in the absence of the Ku heterodimer. Nucl. Acids Res. 31: 5054-5063
Tomita K, Matsuura A, Caspari T, Carr AM, Akamatsu Y, Iwasaki H, Mizuno K, Ohta K, Uritani M, Ushimaru T, Yoshinaga K, Ueno M. (2003)
Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand break, but not telomeres. Mol. Cell. Biol. 23: 5186-5197
原著論文（それ以前の重要なもの）
Matsuura A, Naito T, Ishikawa F. (1999) Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3+ and
tel1+ are parts of two regulatory networks independent of the downstream protein kinases chk1+ and cds1+. Genetics 152: 1501-1512
Shintani T, Mizushima N, Ogawa Y, Matsuura A, Noda T, Ohsumi Y. (1999) Apg10p, a novel protein-conjugating enzyme essential for autophagy in
yeast. EMBO J. 18: 5234-5241
Yamada M, Hayatsu N, Matsuura A, Ishikawa F. (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element is induced in
survivor defective for telomerase. J. Biol. Chem. 273: 33360-33366
Naito T, Matsuura A, Ishikawa F. (1998) Circular chromosome formation in a fission yeast mutant defective in two ATM-homologues. Nat.
Genet. 20: 203-206
Nakayama J, Saito M, Nakamura H, Matsuura A, Ishikawa F. (1997) TLP1: A gene encoding a protein component of mammalian telomerase is
a novel member of WD repeats family. Cell 88: 875-884
Matsuura A, Tsukada M, Wada Y, Ohsumi Y. (1997) Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces
cerevisiae. Gene 192: 245-250
Matsuura A, Anraku Y. (1993) Characterization of the MKS1 gene, a new negative regulator of the Ras-cAMP pathway in Saccharomyces
cerevisiae. Mol. Gen. Genet. 238: 6-16
Matsuura A, Treinin M, Mitsuzawa H, Kassir Y, Uno I, Simchen G. (1990) The adenylate cyclase/protein kinase cascade regulates entry into
meiosis in Saccharomyces cerevisiae through the gene IME1. EMBO J. 9: 3225-3232
